Dr Mark Elliott’s article in the BCMJ’s January/February issue is an earnest, simplified, yet still confounding explanation of CRISPR,[1] an emerging genetic manipulation procedure for patients suffering from certain genetic mutations, including sickle cell anemia and thalassemia. The article is meant for nongeneticist physicians who wish to explain to enquiring patients what the CRISPR procedure is, what it can offer, and what are its practical, ethical, and legal limits.
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