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WorkSafeBC /
BY: Peter Rothfels, MD
April 2011
... use of a sedative-hypnotic medication—a prescription for 1 to 2 days will be covered. • Spinal cord injuries—this ... in treating musculoskeletal chronic pain.[ 1 - 3 ] In addition, no evidence-based clinical practice ...
Clinical Articles /
BY: Andre Mattman, MD, FRCPC
May 2011
... considered in terms of published classification systems.[ 1-3 ] The outcome of this process is a statement of how ... includes blood and urine testing as shown in Table 1 . Lactic acidemia is an important but inconsistent ...
Clinical Articles
May 2011
... 227 X-linked, 4 Y-linked, and 28 mitochondrial disorders.[ 1 ] It would not, therefore, be surprising for family ... disease is relatively common, affecting up to 1 in 5000 people. Mitochondrial dysfunction secondary to ...
Clinical Articles /
BY: Andre Mattman, MD, FRCPC
May 2011
... symptoms that may be more prominent in children.[ 1-5 ] Adult-onset mitochondrial disease often presents in ... elsewhere in this theme issue (see pedigree in Figure 1 of “Primer on mitochondrial disease”), was born at ...
Clinical Articles /
BY: Sandra Sirrs, MD, FRCPC,
May 2011
... and their treatment. The study of Family A ( Figure 1 ), discussed here and elsewhere in the theme issue, shows ... and biochemistry is provided by DiMauro and Schon,[ 1 ] who explain that mitochondria are bound by two ... membranes include carnitine palmitoyltransferase types 1 and 2, which require carnitine as a cofactor. In the ...
Clinical Articles /
BY: Shahul Hameed, MD,
May 2011
... radiation and oxygen pressures decrease life span.[ 1 ] He later specified that oxidative damage to ... most common neurodegenerative disease. Prevalence rates of 1% in the 60-plus age group and 4% among those 80 and over ... for familial ALS is the copper-zinc superoxide dismutase 1 (SOD1), responsible for 15% to 20% of all familial ALS ...
BC Centre for Disease Control /
BY: Jane A. Buxton, MBBS, MHSc, FRCPC
May 2011
... British Columbia in 2008 following an alert from Alberta.[ 1 ] From early 2008 to February 2011, 45 cases were reported ... involving a purpuric eruption on earlobes and cheeks.[ 1 ],[ 6 ] The US recently reported that 69% of cocaine seized ... route of cocaine administration identified by cases.[ 1 ] There are likely additional unreported cases; a review of ...
Council on Health Promotion /
BY: Ray Copes, MD, FRCPC
May 2011
... radiation that ranges from 3 kHz to 300 000 MHz.[ 1-3 ] It is part of the electromagnetic spectrum, with ... to the head was 0.0057 W/kg. This represents less than 1% of the specific energy absorption rate calculated for a typical mobile phone exposure, and well below the 1.6 W/kg limit to the head for uncontrolled exposures.[ 5 ] ...
Letters /
BY: Robert Shepherd, MD
May 2011
... of gout. The doctor prescribed naproxen 500 mg X 30, 1 p.o. t.i.d. A pharmacy issued the tablets. The patient’s ...