... months, and abdominal MRI or ultrasound annually until age 17) demonstrated no recurrence. Her symptoms resolved and she ... (βhCG) was undetectable. Bone age was advanced at 17 years. FDG-PET/CT was negative for metastatic disease in ... with somatic and germline mutations in the SMARCA4 gene.[ 17 ] Functional germ cell tumors (gonadal or extra-gonadal): ...