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Guest editors reply to Drs Sinai, Regenstreif, and Leising

As the guest editors of the two-part Gender-affirming care in BC series, we thank you for your responses.[1-3] In reply, we emphasize that the current standards of care guiding health care providers in BC (Standards of... Read More

Guest editorial: Gender-affirming care in British Columbia, Part 2

Gail Knudson, MD, MEd, FRCPC barbara findlay, MA, LLB, QC Daniel L. Metzger, MD, FAAP, FRCPC The care of transgender and gender-questioning children, especially... Read More

Endocrine treatment of transgender and gender-diverse people

Endocrine therapy is used to change the body’s physical characteristics to reduce gender dysphoria or incongruence. Its use can be considered when a diagnosis of gender dysphoria or incongruence has been made, and the... Read More

Precocious puberty: A red flag for malignancy in childhood

Background Functional solid tumors in childhood can arise from the adrenal glands, gonadal tissue, or extra-gonadal tissues. Although these tumors sometimes present with palpable testicular or abdominal masses, many... Read More

Re: Young adult patients with diabetes presenting to a university health clinic with depression and anxiety

I read with interest the article by Thorpe and colleagues regarding anxiety and depression in young adults with type 1 diabetes in a university clinic setting [BCMJ 2017;59:310-311]. Mental health issues are... Read More

Canadian endocrinologists’ views on growth hormone replacement therapy in adult survivors of pediatric brain tumors following achievement of final height

Background Growth hormone deficiency (GHD) is frequently observed in survivors of pediatric brain tumors who were treated with high-dose cranial radiation therapy (more than 36 Gy). Almost 100% of patients treated with... Read More

Diabetic ketoacidosis in children and adolescents: An update and revised treatment protocol

Canada has one of the highest rates of type 1 diabetes (T1D) in the world. The estimated incidence of T1D in Canadian children aged 0 to 14 years is 21.7 per 100000 per year.[1] Using 2008 census data,[2] prevalence in... Read More

Current approaches to the prevention of type 1 diabetes

Type 1 diabetes (T1D, previously called insulin-dependent or juvenile diabetes) is usually the result of T cell - mediated autoimmune destruction of the insulin-producing beta cells of the pancreas.[1] While T1D... Read More

Promoting the use of influenza vaccine for children at risk of complications

Introduction Influenza virus infections represent the most important cause of acute respiratory illness requiring medical attention beyond infancy. In an 8-year study in Houston, Texas, it was shown that half of school... Read More