Treatment for hip and knee osteoarthritis (OA) aims to reduce pain, maintain or improve function, and, where possible, to slow the progress of the underlying disease. Although no medication has yet been shown to slow the advance of joint pathology in osteoarthritis, pharmacological management remains an integral component of therapy for most patients in the course of their disease.
In order to develop patient-focused evidence-based recommendations for the management of hip and knee osteoarthritis, the Osteoarthritis Research Society International (OARSI) convened a panel of 16 experts from four medical disciplines: primary care, rheumatology, orthopaedics, and evidence-based medicine.
Panel members reviewed existing guidelines for the management of hip and knee osteoarthritis, a highly prevalent cause of pain and disability,[1] along with data published from 1945 to January 2006.[2]
Osteoarthritis (OA) is a noninflammatory form of arthritis. A common misconception is that OA is due solely to wear and tear, since OA is typically a disease of persons in the sixth decade and beyond. “Degenerative arthritis” is often used as a synonym for OA, but OA is not the result of a bland degenerative process; rather, OA involves both degenerative and regenerative processes.
Nonspecific low back pain (LBP) is a common,[1,2] costly,[3-5] and debilitating condition, and to date, management of this disorder remains a challenge.[6,7] While the most recent medical evidence supports moderate physical activity as a valid and durable intervention for LBP, many conventional treatments appear to provide a lack of efficacy or durability. Indeed, for some treatments, including surgery, the risks might outweigh the benefits.