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Clinical Articles / BY: Ian R.A. Mackenzie, MD, FRCPC April 2001
... disease (PD) and the appropriateness of the terminology.[ 1 ] Traditionally, PD has been viewed as a specific entity in ... from the substantia nigra and locus ceruleus  Figure 1 . The caudate, putamen, globus pallidus, thalamus, and ... this indicates that Lewy bodies are not disease specific.[ 1 ] Pale bodies Pale bodies are ill-defined rounded areas of ...
Clinical Articles / BY: Margo R. Fluker, MD, FRCSC November 2001
... either estrogen alone or estrogen plus a progestin. [ 1]  In recent years, standard teaching suggested that HRT ... duration of HRT. In such a model, HRT might be used for 1 to 5 years in the perimenopausal interval to control ... and aging. Vasomotor symptoms Vasomotor symptoms ( Table 1 ) are usually most troublesome in the perimenopause and ...
Clinical Articles / BY: William J. Sullivan, BA, LLB, MCL July / August 2001
... came into force in British Columbia on 28 February 2000.[ 1-4 ] These words and their antonyms are, in practise, used ... In British Columbia, the Representation Agreement Act[ 1 ] governs advance directives. If the patient has made a ... personnel respond to an emergency call. Updated as of 1 June 2001, the directive can now be combined with a “No ...
Letters / BY: Michael Alms, MB March 2001
See responses to this letter:  1 ,  2 One often hears the claim that in Canada we enjoy the ...
Clinical Articles / BY: R.C. Offer, MD, FRCPC, FACR October 2001
... costs of osteoporosis in Canada were estimated to be $1.3 billion. [ 1]  Increasing longevity and rising numbers of aging baby ... review of the woman’s lifestyle and risk factors ( Table 1 ). Modification of these risks, where possible, is ...
Clinical Articles / BY: A. Jon Stoessl, MD, FRCPC May 2001
... in the basal ganglia that is disrupted in PD. [1]  However, these medications are also known to inhibit ... 15 mg to 40 mg/day) and pergolide (Permax) (usual dose 1.5 mg to 4.5 mg/day). These compounds are both ergot ... in patients with early PD. Both pramipexole (usual dose 1.5 mg to 4.5 mg/day) and ropinirole (usual dose 9 mg to 24 ...
Editorials / BY: James A. Wilson, MD January/February 2001
According to most sieclephiles, 1 January 2001 is the real start of the new millennium, so I ...
Clinical Articles / BY: Janet Henderson, MB, BCh September 2001
... synthesis. There are two isoforms of this enzyme: COX-1 and COX-2. [1]  COX-1 is constitutively expressed and generates prostaglandins ...
Editorials / BY: James A. Wilson, MD April 2001
... party and I came to a fairly quick agreement and as of 1 January 2001 I started a sabbatical for 6 to 12 months. ...
Clinical Articles November 2001
... for “Exposure to Biological Agents Response Plan”  [1]   to assist medical health officers and other regional ... (e.g., household 5% bleach, diluted 10 parts water to 1 part bleach) and finally rinsed with water to minimize skin ...