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Clinical Articles / BY: Colin Mar, MD, FRCPC January/February 2018
... now stands at 16 per 100 000 in BC. The age-standardized 5-year relative survival ratio for 2006 to 2008 was 88% ... in younger women and those with dense breast tissue.[ 5 ] Evidence for screening mammography   The evidence for ... positive predictive value in the SMP for first screens was 5.2% and for subsequent screens was 7.0%, values that both ...
Clinical Articles / BY: Christine Wilson, MD, FRCPC January/February 2018
... of very successful programs already operating in Europe.[ 5 ] Implementation of the clinical pathway was facilitated by ... 95% had their diagnostic studies at one centre (MSJ) and 5% had diagnostic studies at other centres. In contrast, only ... ultrasound, and ultrasound-guided core biopsy, 31.5% attended more than one diagnostic centre. In 2010 the ...
Clinical Articles / BY: Amie Padilla-Thornton, MD, FRCPC January/February 2018
... than or equal to 95% risk). Lesions assessed as BI-RADS 5 have an estimated risk of malignancy greater than 95%, ... 2% likelihood of being malignant (BI-RADS 4 or BI-RADS 5), and an image-guided biopsy is required for definitive pathologic diagnosis.  5.    Depending on the presenting compliant, referral to a ...
Clinical Articles / BY: Katherine A. Blood, MD, PhD January/February 2018
... are thought to occur sporadically, with approximately 5% thought to be due to inherited susceptibility to cancer.[ ... cancer and genetics, and help reduce patient stress.[ 5 ] Women who have an increased risk of breast cancer due to ... for these mastectomies are presented in ( Table 5 ). The mean age of patients undergoing bilateral mastectomy ...
Clinical Articles / BY: Heather E. Cadenhead, BKin January/February 2018
... was 29.8 (SD 14.8) years. The youngest patient was 5 years old and the oldest was 64 years old. The male to ... posterior synechiae, cataracts, and optic nerve damage.[ 5,6 ] Other posterior segment injuries that may occur as a ... such as anesthetic eye drops (e.g., tetracaine 0.5%) and cycloplegics (e.g., cyclopentolate 0.5%) for ...
Clinical Articles / BY: Rebecca Warburton, MD, FRCSC March 2018
... breast reconstruction for woman who require mastectomy.[ 5,6 ] Because definitive treatment of breast malignancy ... techniques have developed to allow BCS in larger tumors.[ 5 ] Another option for some women motivated to undergo breast ... acceptable oncologic and cosmetic outcomes after BCS.[ 5,14,15 ] The main challenge presented by BCS is the need for ...
Clinical Articles / BY: John A. Taylor, MD, MPH, FRCPC March 2018
... provided free for high-risk groups in British Columbia.[ 5 ] In one case-control study, influenza vaccination was ... influenza ( Table 4 ) and for pneumococcal disease ( Table 5 ) were varied, with “Do not think I am at high risk” ...
Clinical Articles / BY: F. Michelle Sutter, MD, FRCSC March 2018
... with a reduction in breast cancer mortality of as much as 5%.[ 4 ] While there is some controversy in the setting of ... results in a reduction in breast cancer recurrence, with a 5% improvement in disease-free survival although not in overall survival.[ 5 ] Similar benefit is also seen in the postmastectomy ...
Clinical Articles / BY: Connie G. Chiu, MD, FRCSC March 2018
... lymph node dissection (ALND) is 20%, compared with 5% for sentinel lymph node biopsy (SLNB).[ 1 ] However, a ... the presence of severe edema alone (defined as more than a 5-cm difference in arm circumference), which has an estimated incidence of 3.0% for ALND and 0.5% for SLNB.[ 2 ] The use of axillary radiation is an ...
Clinical Articles / BY: Christine E. Simmons, MD, MSc, FRCPC March 2018
... has spread to the regional lymph nodes, tumors larger than 5 cm, or high-risk features such as estrogen receptor ... by four cycles of doxorubicin and cyclophosphamide.[ 5 ] The study found that postponing surgery until after ... of patient outcomes. Outcomes As Wolmark and colleagues[ 5 ] demonstrated in 2001, patients who experience a ...