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Clinical Articles / BY: Ken Seethram, MD, FRCSC, FACOG June 2018
... states) can be detected by prenatal screening.[ 4 ]  Serum and ultrasound markers Maternal serum screening ... 21, 18, and 13 first became available in the 1980s.[ 4 ] The sensitivity and specificity of screening improved as ... the major aneuploidies of chromosomes 21, 18, and 13.[ 4 ] Then, additional ultrasound markers (e.g., uterine artery ...
Clinical Articles / BY: Daniel Shearer, BSc June 2018
... be achieved safely without undue risk of hypoglycemia.[ 4 ] Above 7.0%, adverse outcomes increase by approximately ... ]  The safety of newer OHAs such as dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose linked transporter 2 (SGLT2) ...
Clinical Articles / BY: Elizabeth Taylor, MD, FRCSC June 2018
... notes that miscarriages can cause considerable distress.[ 4 ] Although common, recurrent miscarriage is neither well ... decrease in the early miscarriage rate from 89.6% to 12.4%, as well as an increase in term delivery rate from 1.4% to 74.4%.[ 9 ] Uterine fibroids and endometrial adhesions ...
Clinical Articles / BY: Constantin Shuster, MD June 2018
... readmissions affect almost 200 000 Canadians annually.[ 4 ] Unfortunately, British Columbia’s 2016 risk-adjusted ... per year, which represents 11% of annual inpatient costs.[ 4 ] Moreover, the average cost of a second hospitalization is ... the first ($10 404 versus $7287 for medical patients).[ 4 ] Hospital readmissions may be complicated by iatrogenic ...
Clinical Articles / BY: Jeffrey Roberts, MD, FRCSC May 2018
... granulosa cells, and disappearance of eggs.[ 3 , 4 ] The toxicity of chemotherapeutic treatments varies ... despite the resumption of regular menstrual cycles.[ 4 , 11-15 ] A survey of 2532 cancer survivors between the ...
Clinical Articles / BY: Caitlin Dunne, MD, FRCSC May 2018
... ability to fertilize a human egg in vitro after 5 days.[ 4 , 5 ] Following ovulation, an egg may be ready for ... patients since levels must be obtained on cycle days 2 to 4 and are prone to intercycle fluctuations. For this reason, ... motility (32%), vitality (58%), and morphology (4%).[ 43 ] For fertility, the chief prognostic parameters are ...
Clinical Articles / BY: Jason Wong, MD, MPH, CCFP, FRCPC May 2018
... increasingly common in North America[ 1-3 ] and Europe[ 4-7 ] among gay, bisexual, and other men who have sex with ... rectal chlamydia samples was implemented, then fell to 6.4% in 2012 to 2014 ( Table 2 ). Overall, the positivity rate ... cases reported for MSM in other jurisdictions.[ 1 , 2 , 4-7 ] Characteristics and risk factors for LGV cases reported ...
Clinical Articles / BY: Jon Havelock, MD, FRCSC May 2018
... of ovarian hyperandrogenism[ 3 ] and insulin resistance.[ 4 ] Evidence suggests that the ovarian hyperandrogenism in ... cell ovarian androgen production in concert with LH,[ 4 ] and indirectly by lowering sex hormone-binding globulin, ... 24 ] Subjects in the lifestyle intervention group lost 4.4 kg on average during the 6-month pre-fertility treatment ...
BC Centre for Disease Control / BY: Monika Naus, MD, MHSc, FRCPC, FACPM May 2018
... of immunization: for RotaTeq, is three  doses, at 2, 4, and 6 months of age, whereas for ROTARIX, it was two  doses at 2 and 4 months of age. The series can be started as early as 6 ... following introduction of rotavirus vaccine.[ 4 ] Finally, it is important for providers to be aware that ...
Council on Health Promotion / BY: Charuka Maheswaran, MBBS, DTM&H, DRCOG, DFFP, PMETB, CELTA, LMCC, CCFP, MPH May 2018
... Aboriginal Peoples and the Auditor General of Canada.”[ 4 ] Boyd also comments that there are no national standards ... are guidelines for provinces to apply as they see fit.[ 4 ] Because of the Canada Labour Code, Health Canada has ... Indigenous communities with poor water quality.[ 4 ] Poor infrastructure and poverty are seminal causes of ...