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Clinical Articles / BY: Donald B. Calne, OC, DM April 2001
... bodies,[ 3 ] and subacute sclerosing panencephalitis.[ 4 ] We also know that some patients who fulfill all the ...
Clinical Articles / BY: Ian R.A. Mackenzie, MD, FRCPC April 2001
... to be highly sensitive and specific markers (see below).[ 4 ] Brainstem Lewy bodies are not specific to PD; they have ... demonstrated using ubiquitin immunohistochemistry  Figure 4 . They are most concentrated in a sub-region of the ... bodies as well as pale bodies and Lewy-related neurites.[ 4,13 ] Biochemical abnormalities in the PD brain Degeneration ...
Editorials / BY: James A. Wilson, MD April 2001
... reminded me that, during a moment of weakness about 4 weeks earlier, I had agreed to work Saturday. I hauled my ...
Clinical Articles / BY: T.A. Hurwitz, MBChB, MRCP, FRCPC May 2001
... of the parkinsonian motor symptoms is necessary. [4]  Patients with a prior history of depression are more ... by the presence of chronic hallucinations and delusions. [4]  Psychosis most commonly occurs in patients who have ...
Clinical Articles / BY: Chong S. Lee, MD, FRCPC May 2001
... were made in primates with unilateral 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) lesions. [4]  In contrast, primates with intact nigrostriatal ...
Clinical Articles / BY: Christopher R. Honey, MD, DPhil, FRCS May 2001
... reduced in 78% of PD patients following pallidoansotomy. [4]  Reports of reduced tremor and improved rigidity after ...
Clinical Articles / BY: Christopher Bozek MD, FRCPC May 2001
... in PD patients taking calcium channel blockers. Lees [4]  reported increased cardiac mortality in patients with PD ...
Clinical Articles / BY: A. Jon Stoessl, MD, FRCPC May 2001
... predictor of prolonged survival in patients with PD). [4]  Therefore it is an entirely legitimate choice for ... to 40 mg/day) and pergolide (Permax) (usual dose 1.5 mg to 4.5 mg/day). These compounds are both ergot derivatives. In ... with early PD. Both pramipexole (usual dose 1.5 mg to 4.5 mg/day) and ropinirole (usual dose 9 mg to 24 mg/day) are ...
Clinical Articles / BY: Helena H. Ho, MD, FRCPC June 2001
... [1,2]  The prevalence has increased over the years from 4 to 5 per 10,000 to 1 in 500. [3,4]  These markedly increased prevalence rates may reflect ...
Clinical Articles / BY: Stuart Fine, MB, FRCPC June 2001
... has been adequately demonstrated in the literature, [4,5]  and to a lesser degree with adolescents,  [6]  there ... 20% of families stopped taking the medication after 4 months and 44% after 10 months despite positive reports of ... helpful at the clinic. The interviews took place within 4 weeks of mailing the letter. Results Chi-square (χ2) tests ...