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Clinical Articles / BY: Edith McGeer, PhD April 2001
... disease (AD), where it has been extensively studied,[ 1,2 ] but there is also evidence suggesting that a local immune ... with controls. Preliminary results are shown in  Figure 2 .[ 16 ] The messenger ribonucleic acids for all components ...
Clinical Articles / BY: Donald B. Calne, OC, DM April 2001
... occur in such disorders as Hallervorden-Spatz disease,[ 2 ] dementia with Lewy bodies,[ 3 ] and subacute sclerosing ...
Clinical Articles / BY: Ian R.A. Mackenzie, MD, FRCPC April 2001
... ventral tier of the pars compacta being most affected.[ 2 ] It is estimated that at least 50% of the nigral neurons ... are an age-related incidental autopsy finding occurring in 2% to 10% of neurologically normal individuals. While some ... that such individuals may have presymptomatic PD,[ 2,5 ] others feel this indicates that Lewy bodies are not ...
Editorials / BY: James A. Wilson, MD April 2001
... It was 5:30 Friday afternoon and I was looking forward to 2 days of needed rest. My reverie was suddenly shattered when ...
Letters / BY: Sterling Haynes, MD April 2001
... subject, see 2000;42(5):224, 2000;42(10):466, and 2001;43(2):94. —Ed Letters Environment and health—go green ...
Letters / BY: Lorna Sent, MD April 2001
... initiative in place, the Asian Women’s Health Clinic,[ 2 ] that addresses these barriers. This clinic provides ...
Clinical Articles / BY: T.A. Hurwitz, MBChB, MRCP, FRCPC May 2001
... tensions at a time when a patient most needs support. [2,3]  Depression may precede the diagnosis of PD, sometimes ... family, and other caregivers, treatment is impossible. [2]  Psychological support All patients, but especially ... night increasing to 25 mg at night, [20]  or olanzapine 2.5 mg at night increasing to 10 mg at night. [21] ...
Clinical Articles / BY: Chong S. Lee, MD, FRCPC May 2001
... neurons, and exogenous administration of levodopa. [2] Nigrostrial dopamine denervation Levodopa-induced ... were made in primates with unilateral 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) lesions. [4]  In contrast, ...
Clinical Articles / BY: Christopher R. Honey, MD, DPhil, FRCS May 2001
... reviews on the history of neurosurgery for PD. [1,2]  In British Columbia, the surgical treatment of PD was ... demonstrated continued efficacy for off-period signs at 2- and 3-year follow-up. [13]  The potential complications ...
Clinical Articles / BY: Christopher Bozek MD, FRCPC May 2001
... their blood pressure monitored. Hillen and colleagues [2]  found that subclinical (decrease of systolic BP >15 mm ... and Parkinson's disease. Parkinsonism Rel Disord 1996;2:177-187. Mason LJ, Cojocaru TT, Cole DJ. Surgical ...