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Clinical Articles / BY: H. Grant Stiver MD, FRCPC January/February 2000
... age groups and by 40% in elderly nursing home residents.[ 2 ] In spite of this, surveys indicate that even in patient ... (Tamiflu). Zanamivir was granted Health Canada approval on 2 November 1999 and oseltamivir on 24 December 1999. Both are ... Evidence for antiviral drug treatment of influenza Table 2  lists efficacy of amantadine and the antiviral agents ...
Clinical Articles / BY: Danuta M. Skowronski, MD, FRCPC January/February 2000
... be very high, reaching up to 60% to 70% of residents[ 1 , 2 ] with case fatality rates as high as 30%.[ 3 ] Infection ... days but cough, malaise, and lethargy may persist for 1 to 2 weeks after the fever has resolved.[ 7 ] For the purpose of ... be considered. Amantadine should be continued for at least 2 weeks or until approximately 1 week after the onset of the ...
Clinical Articles / BY: Leila Srour, MD January/February 2000
... cope with selective immunologic and drug pressures.[ 1 , 2 ] Influenza viruses have unique genomic properties, ... preceded the ILI outbreaks in health-care facilities by 2 weeks. Peak ILI activity in schools coincided with the peak ... that reported no amantadine use (RR 1.48, CI 1.06<;RR<;2.05). In extended-care facilities, increased risk of death ...
Editorials / BY: Danuta M. Skowronski, MD, FRCPC January/February 2000
... to cause severe disease and death in young adults.[ 2 ] The most recent pandemic occurred in 1968, and experts ... will need to be administered to Canadians within a 1 to 2 month period. This figure represents five to ten times the ...
Clinical Articles / BY: Gordean Bjornson, MBA March 2000
... children the infection rate was about 30% each year.[ 1,2 ] The complications of influenza generally result from ... of influenza vaccine for household members in 1998 was 42.2% for diabetics and 46.7% for asthmatics. In ...
Clinical Articles / BY: Danuta M. Skowronski, MD, FRCPC March 2000
... also recommends immunization for health-care workers.[ 1 , 2 ] A distinct recommendation to health-care workers has been ...
Editorials / BY: Danuta M. Skowronski, MD, FRCPC March 2000
... Vancouver Editorials Influenza: The elusive plague—Part 2 (Guest editorial) ...
Clinical Articles / BY: Alex Agranovich, MD, FRCPC April 2000
... form of radiotherapy was pioneered by Dr J. Papillon.[ 2 ] Only a small fraction of patients with rectal cancer are ... (five treatments over 1 week) followed by radical surgery 2 weeks later was compared with surgery alone. With median ... of radiotherapy is sufficient (from a single treatment to 2 weeks of treatment). Radiotherapy is not advised, however, ...
Clinical Articles / BY: Iain G.M. Cleator, MB, CHB, FRCSC, FRCSE, FRCS, FACS April 2000
... at least 6 years for this transformation to occur.[ 1,2 ]  Under current accepted standards of screening and ... compliant was 44%. Interestingly, the group screened every 2 years had a reduction in mortality of 6%. The rate of ... without rehydration in a screening program conducted every 2 years. Their colonoscopy rate was 4.3%. The predicted ...
Clinical Articles / BY: Greg Hislop, MD April 2000
... rates for CRC are among the highest in the world,[ 2 ] being surpassed only by lung, female breast, and prostate ... from 1986 to 1993, and in mortality of -1.4% and -2.5%, respectively, from 1986 to 1995. Previously, incidence ...