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Clinical Articles / BY: Amil Shah, MDCM, FRCPC, FACP May 2000
... of life. Thymidylate synthase inhibitors Until recently, 5-fluorouracil (5FU) was the only drug with any track record ... of administration of 5FU is by a rapid bolus injection for 5 consecutive days every 4 weeks (Mayo regimen),[ 3 ] but ... survival benefits are inconsistent from study to study.[ 5 ]  A variation on this theme is hepatic arterial perfusion ...
Clinical Articles / BY: Greg McGregor, MD, FRCSC May 2000
... do not exceed 1 cm of distal submucosal extension.[ 5 ] Cancer of the upper third of the rectum should be ... excision; the distal rectal resection margin should be 5 cm with accompanying subtotal mesorectal resection of at least 5 cm from the distal edge of the tumor. Tumors at or just ...
Clinical Articles / BY: David Baxter June 2000
... past century, the 65-plus population has increased from 5% of Canada’s population to its record of 12% today (see  ... 140 000 additional people per year, contributing only a 0.5% increase to a population of 30 million. If Canada can ...
Clinical Articles / BY: Danuta M. Skowronski, MD, FRCPC June 2000
... may be necessary where homes are already inhabited.[ 5 ] What is the risk associated with bats? Bat rabies was ... gloves should be worn if direct contact is a possibility.[ 5 ] Since the brain and/or spinal cord are required for ... a person previously unimmunized against rabies consists of 5 spaced doses of human diploid cell rabies vaccine (given on ...
Clinical Articles / BY: Angus Rae, MB, FRCPC June 2000
... Clinical Faculty Association was formed in March 1998.[ 5 ] Clinical faculty have a plethora of role models with ...
Clinical Articles / BY: Kendall Ho, MD, FRCPC June 2000
... the growth of telemedicine over the next several years.[ 5-8 ] Whereas currently, rural physicians often operate ...
Clinical Articles / BY: Martin Zelder, PhD June 2000
... coinsurance rates—0% to 95%—and their deductibles—5%, 10%, or 15% of family income, up to a maximum of $1000 ... figures are in $US). The families were followed for 3 to 5 years in order to understand how assignment to different ...
Editorials / BY: David Doty, MD June 2000
... we have no nurses for the ORs or the ICUs. In the next 5 years, we will have no doctors either. The average age of a ... replace them. Because of government policies, in the next 5 years here in Victoria, we will probably not have a ...
Clinical Articles / BY: Robert T. Morrison, MD, FRCPC July/August 2000
... 1 standard deviation below this, and a T-score of –2.5 has been designated by WHO as representing osteoporosis.[ 2 ... Only one patient (0.1%) who had a BMD T-score of –2.5 SD would have been missed had the SCORE index been used as ... (22.3% of the total) who had a T-score of >–2.5, i.e., non-osteoporotic, could have been excluded by ...
Clinical Articles / BY: Harvey Thommasen, MD, MSc, FCFP July/August 2000
... time” in rural communities have not yet worked.[ 1,2,3,4,5,6,7 ] Review of the literature reveals that the problem of ... 17 communities with populations between 3500 and 6999, 5 communities with populations between 7000 and 10999, 8 ... than 7000 people. The differences are clearly apparent by 5 years, and remain pretty much throughout the 21 year study ...