Reporting in BC laboratories: Transition to new formulas
BC introduced estimated glomerular filtration rate (eGFR) reporting in 2004 as per international recommendations to facilitate early recognition of patients with chronic kidney disease. Currently all laboratories in BC report eGFR values whenever a serum or plasma creatinine is ordered on an ambulatory patient. As of 15 December 2014, all BC chemistry laboratories calculate and report eGFR values using a new set of improved formulas. Specifically, the internationally endorsed formula entitled the chronic kidney disease epidemiology collaboration formula (CKD EPI) eGFR will replace the previously used MDRD formula. This new calculation for eGFR values will not change the manner in which they are interpreted: they are interpreted in conjunction with the urinary albumin measurement as a means to detect and manage chronic kidney disease (www.bcguidelines.ca/pdf/ckd.pdf). If you have questions about this change, contact your local laboratory’s medical director.