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Sandra Sirrs, MD, FRCPC,
Mitochondria are intracellular organelles that make energy through processes requiring oxygen. Primordial eukaryotic cells were initially anaerobic before they developed a symbiotic relationship with bacteria that could... Read More
Mitochondrial diseases are heterogeneous and multifaceted, and can present at any age. Clinical features may range from an acute life-threatening metabolic derangement to intermittent or episodic crises with partial... Read More
Mitochondrial disease is a clinically heterogeneous, often multisystem disorder that can present from birth to old age. Diagnosis is complex and requires the integration of information obtained by history, laboratory... Read More