The Personalized Onco-Genomics (POG) program at the BC Cancer Agency is a clinical research program bringing genomic sequencing directly into patient care for those with incurable cancers. POG was launched in 2012, and more than 170 patients have taken part to date.
Oncologists and scientists at the BC Cancer Agency work collaboratively on POG to sequence the patient’s tumor and healthy DNA, compare the results, determine what’s biologically driving the patient’s cancer, and identify potential treatments. The program is a leading clinical research initiative with genomic science informing chemotherapy decision making in the routine clinical care of patients with metastatic cancers.
Each patient taking part in POG is in a personalized clinical trial where science is translating into care and providing research data that may benefit other cancer patients in BC and around the world.
The POG program was in the news recently when it identified a novel treatment option for a patient with advanced cancer. The genomic sequencing of Ms Trish Keating’s aggressive colorectal cancer identified a unique protein function at play. This critical detail pointed to an unusual treatment option, which dramatically reduced her cancer to barely detectable in just weeks.
The POG program is funded entirely by the BC Cancer Foundation. The Foundation’s 2014 Inspiration Gala raised over $5 million in support of POG, and the Foundation has committed $12.5 million to fund POG, which will see over 300 patients enter the program.
Above is the information needed to cite this article in your paper or presentation. The International Committee
of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally
accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.
About the ICMJE and citation styles
The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.
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For more information on the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, visit www.icmje.org