The topics discussed in this issue provide the platform upon which modern medical management for Parkinson’s disease is built, and from which we can expect new directions of management to emerge.... Read More

Introduction As described in Dr Calne’s article there is currently some controversy as to what is meant by Parkinson’s disease (PD) and the appropriateness of the terminology.[1]... Read More

Introduction Parkinson’s disease (PD) is one of the most common age-related neurodegenerative disorders, second in frequency only to Alzheimer’s disease. In the United States, at least half a... Read More

Introduction The functional capabilities of positron emission tomography (PET) and single photon emission tomography (SPECT) are among the most useful and revealing techniques to image the brain in... Read More

Introduction Classical dogma taught that the brain is immunologically privileged and does not mount an endogenous immune response. Immunohistochemical and molecular biological evidence accumulated... Read More